PPI Medications Linked To “Silent” Kidney Damage More than 20 million Americans fill prescriptions for proton pump inhibitor (PPI) medications each year in the United States, according to the U.S. Food and Drug Administration (FDA). Approved for the treatment of gastric-acid illnesses, such as chronic heartburn, peptic ulcer disease (PUD), gastroesophageal reflux disease (GERD), and […]
PPIs Linked To Increased Risk Of Heart Failure And Death In Patients With CAD Patients with coronary artery disease (CAD) rely on chronic antiplatelet therapy to mitigate the risks associated with their disease. These therapies often include aspirin and Plavix® (clopidogrel), both of which are notorious for causing gastrointestinal complications. Aspirin puts patients at risk for gastrointestinal ulcers and […]
Study Offers Clues To How PPIs Damage Arteries Over Time Previous research into the efficacy and safety of acid-reducing proton pump inhibitors (PPIs) suggested a link between long-term use and a myriad of serious health problems, including artery damage and cardiovascular disease. However, until recently, researchers weren't able to explain how these drugs might inflict this damage. A 2016 […]
Hip Implant Recalls Negatively Affect Stryker Q4 Earnings Stryker has come under fire in recent years for metal-on-metal hip replacement systems that fail prematurely, necessitating painful and invasive hip replacement or reconstructive surgeries. After voluntarily recalling two such components—the Rejuvenate and ABG II modular-neck hip stems—in 2012 over concerns of fretting and corrosion, the problematic devices are finally […]
Bleeding-Related Costs Lower With Eliquis® Than Rivals Pradaxa® In a recent real-world study comparing the benefits of old-school warfarin and next-generation anticoagulants Eliquis (apixaban), and Pradaxa (dabigatran) for the treatment of non-valvular atrial fibrillation, Eliquis repeatedly came out on top in terms of efficacy, safety, and controlling bleeding-related costs. The study was presented at the American […]
Alternatives To Proton Pump Inhibitors For Heartburn Relief Proton pump inhibitors (PPIs) such as Prilosec® (omeprazole), Prevacid® (lansoprazole), and Nexium® (esomeprazole) decrease stomach acid by inhibiting the enzyme responsible for its production, effectively treating a variety of peptic acid disorders, such as chronic heartburn and gastroesophageal reflux disease (GERD). Although quite adept at controlling stomach acid, PPIs have […]
Alternatives To Metal-On-Metal Hip Implants When natural hip joints fail due to overuse, arthritis, or injury, people often experience excruciating pain and severely limited mobility. For many, a total hip replacement surgery is the answer. In the past, this surgical procedure was reserved for elderly patients, but now patients are much younger, wanting to the […]
Finnish Study Links Childhood Asthma Risk To PPI Use During Pregnancy Proton pump inhibitors, or PPIs, such as Prilosec® (omeprazole) and Nexium® (esomeprazole) are used to treat peptic-acid disorders, including gastroesophageal reflux disease (GERD), peptic ulcer disease (PUD), nonsteroidal anti-inflammatory drug-induced gastropathy and chronic heartburn. While PPIs are quite effective at banishing unwanted stomach acid, they've also been […]
Study Finds Pradaxa® Bleeding Risks Increase With Certain Statins Pradaxa (dabigatran etexilate mesylate), a widely-prescribed anticoagulant medication manufactured by German pharmaceutical company Boehringer Ingelheim. It's used to prevent dangerous blood clots and strokes in patients with atrial fibrillation, a heart condition characterized by a rapid and irregular heartbeat. Despite its popularity and proven efficacy, Pradaxa is linked to […]
What Are The Long-Term Effects Of Taking PPIs? Since their approval by the U.S. Food and Drug Administration (FDA) in 1989, proton-pump inhibitors (PPIs) have proven effective in treating chronic heartburn, peptic ulcer disorder (PUD), gastroesophageal reflux disease (GERD) and nonsteroidal anti-inflammatory drug-induced gastropathy. However, studies link long-term use of these drugs to a number […]
PPI Medications Linked To “Silent” Kidney Damage More than 20 million Americans fill prescriptions for proton pump inhibitor (PPI) medications each year in the United States, according to the U.S. Food and Drug Administration (FDA). Approved for the treatment of gastric-acid illnesses, such as chronic heartburn, peptic ulcer disease (PUD), gastroesophageal reflux disease (GERD), and […]
PPIs Linked To Increased Risk Of Heart Failure And Death In Patients With CAD Patients with coronary artery disease (CAD) rely on chronic antiplatelet therapy to mitigate the risks associated with their disease. These therapies often include aspirin and Plavix® (clopidogrel), both of which are notorious for causing gastrointestinal complications. Aspirin puts patients at risk for gastrointestinal ulcers and […]
Study Offers Clues To How PPIs Damage Arteries Over Time Previous research into the efficacy and safety of acid-reducing proton pump inhibitors (PPIs) suggested a link between long-term use and a myriad of serious health problems, including artery damage and cardiovascular disease. However, until recently, researchers weren't able to explain how these drugs might inflict this damage. A 2016 […]
Hip Implant Recalls Negatively Affect Stryker Q4 Earnings Stryker has come under fire in recent years for metal-on-metal hip replacement systems that fail prematurely, necessitating painful and invasive hip replacement or reconstructive surgeries. After voluntarily recalling two such components—the Rejuvenate and ABG II modular-neck hip stems—in 2012 over concerns of fretting and corrosion, the problematic devices are finally […]
Bleeding-Related Costs Lower With Eliquis® Than Rivals Pradaxa® In a recent real-world study comparing the benefits of old-school warfarin and next-generation anticoagulants Eliquis (apixaban), and Pradaxa (dabigatran) for the treatment of non-valvular atrial fibrillation, Eliquis repeatedly came out on top in terms of efficacy, safety, and controlling bleeding-related costs. The study was presented at the American […]
Alternatives To Proton Pump Inhibitors For Heartburn Relief Proton pump inhibitors (PPIs) such as Prilosec® (omeprazole), Prevacid® (lansoprazole), and Nexium® (esomeprazole) decrease stomach acid by inhibiting the enzyme responsible for its production, effectively treating a variety of peptic acid disorders, such as chronic heartburn and gastroesophageal reflux disease (GERD). Although quite adept at controlling stomach acid, PPIs have […]
Alternatives To Metal-On-Metal Hip Implants When natural hip joints fail due to overuse, arthritis, or injury, people often experience excruciating pain and severely limited mobility. For many, a total hip replacement surgery is the answer. In the past, this surgical procedure was reserved for elderly patients, but now patients are much younger, wanting to the […]
Finnish Study Links Childhood Asthma Risk To PPI Use During Pregnancy Proton pump inhibitors, or PPIs, such as Prilosec® (omeprazole) and Nexium® (esomeprazole) are used to treat peptic-acid disorders, including gastroesophageal reflux disease (GERD), peptic ulcer disease (PUD), nonsteroidal anti-inflammatory drug-induced gastropathy and chronic heartburn. While PPIs are quite effective at banishing unwanted stomach acid, they've also been […]
Study Finds Pradaxa® Bleeding Risks Increase With Certain Statins Pradaxa (dabigatran etexilate mesylate), a widely-prescribed anticoagulant medication manufactured by German pharmaceutical company Boehringer Ingelheim. It's used to prevent dangerous blood clots and strokes in patients with atrial fibrillation, a heart condition characterized by a rapid and irregular heartbeat. Despite its popularity and proven efficacy, Pradaxa is linked to […]
What Are The Long-Term Effects Of Taking PPIs? Since their approval by the U.S. Food and Drug Administration (FDA) in 1989, proton-pump inhibitors (PPIs) have proven effective in treating chronic heartburn, peptic ulcer disorder (PUD), gastroesophageal reflux disease (GERD) and nonsteroidal anti-inflammatory drug-induced gastropathy. However, studies link long-term use of these drugs to a number […]
